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Hypoxia at the site of inflammation stimulates FLS to produce messenger RNAs such as CXCL12 and VEGF, resulting in a 50% and 132% increase in the protein levels of VEGF and CXCL12, respectively, after 24 hours of hypoxia (135)

Larger high-quality studies are needed

The association between intake of dietary lycopene and other carotenoids and gestational diabetes mellitus risk during mid-trimester: A cross-sectional study

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Currently, CRISPR-based strategies for secondary metabolite research typically involve knocking out or significantly altering the expression of target genes, rather than enabling precise regulation