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they also found that SFXN1-null cells manifested a proliferation defect in the absence of l-serine, suggesting that it plays a role in serine transport

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The moderate suppression of the TCA cycle and OXPHOS reduces mitochondrial ROS production and inhibits cell death [71]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 60.Wang T., Arifoglu P., Ronai Z., Tew K.D

Polymorphism G80A in the reduced folate carrier gene and its relationship to methotrexate plasma levels and outcome of childhood acute lymphoblastic leukemia