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The lesion showed intense heterogenous contrast enhancement and caused a massive perilesional spinal cord edema extending from the medulla oblongata to the level of C6 (Fig

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The drug had good safety, tolerability, pharmacokinetic and pharmacodynamic profiles.[11,25] In a double-blind, randomized Phase I trial in 40 healthy male volunteers, six subjects each received SLx-2101 at 5, 10, 20, 40 or 80 mg and ten subjects received placebo

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After obtaining the baseline electrical field stimulation frequency responses as outlined above, the tissues were treated with vehicle or MT-II (10 M) and incubated for 30 min