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To study the role of IGF-I uptake in bone elongation, Serrat and Ion [241] developed methods for visualizing the transport of fluorescently-labeled, biologically-active IGF-1 into the proximal tibial growth plate of live young mice using MPM

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For linker design, the use of shorter, more rigid, all-carbon linkers, as opposed to flexible or PEG-based ones, has been shown to enhance permeability, stability, and reduce efflux susceptibility 225

four included adult and paediatric patients

We applied conditional logistic regression to appraise the risk and Cox proportional hazards models to appraise the prognostic value of IGF-1

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