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Biologically important metal coordination complexes: (Left) Heme, the "business end" of hemoglobin

These may include headaches, nausea, injection site reactions since its administered via a subcutaneous injection, water retention, and altered cortisol levels

Patients should be referred urgently if they have neurological symptoms, if the diagnosis is unclear, or if there is inadequate clinical response to treatment

Persistent side effects beyond 2 weeks after a dose increase Transient nausea, mild constipation, and decreased appetite are expected and normal during the 1 to 2 weeks after each dose increase

Goes systemically in the bloodstream