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Description
The effects of the leptin-GLP-1 interaction may be governed by intracellular signaling pathways, including those involving phosphorylated STAT3 and PTP1B

10.1038/s43587-025-00816-2 82 SelaM.PoleyM.Mora-RaimundoP.KaganS.AvitalA.KaduriM.et al (2023)

Trial SURPASS-5 (JAMA 2022) Population 475 adults with T2D + insulin glargine

Some patients and athletes report faster pain relief and improved mobility within two to six weeks of use, but these accounts lack the scientific rigor of randomized, controlled studies
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doi: 10.1152/jn.00207.2001

Similar studies have been performed in various other groups, including obese patients
