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In addition to acting as the bodys principal methyl donor, SAMe can play an important role in regulating the methylation status in any given cell type

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Excess vitamin B12 is linked to increased cancer growth in certain types of cancer.[ref] Methotrexate, a chemotherapy drug, works by inhibiting the production of methyl folate, thus limiting methionine and DNA synthesis for cell growth

Autistic children usually have autonomic dysfunction which means they may find it hard to sleep and have a lack of heart rate regulation when exposed to stressful or overwhelming stimuli