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39 It has been suggested that those desmoplastic melanomas having foci of conventional vertical growth phase melanoma manifest a significantly worse prognosis, with regional lymph node metastases in 10% of cases as opposed to only 1% of patients with pure desmoplastic melanoma

doi:10.1016/j.intimp.2015.04.015

Evidence supporting these guidelines continues to grow, and the safety of metabolic surgery has increased over the past two decades (Arterburn 2020)
