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Roberts AW, Davids MS, Pagel JM, Kahl BS, Puvvada SD, Gerecitano JF, et al
Yang ZH, Liu F, Zhu XR, Suo FY, Jia ZJ, Yao SK
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10.1016/j.tips.2013.01.001 4 BodeD
FoxO transcription factors regulate numerous genes coding for intra- and extracellular antioxidant proteins such as Mn-SOD and Cu,Zn-SOD, peroxiredoxin-3 and peroxiredoxin-5, mitochondrial thioredoxin (Trx2) and mitochondrial thioredoxin reductase, glutathione peroxidase 1, and selenoprotein P [143]
To determine the degree of adherence to treatment (and thus avoid outcome dilution effects) [41], the number of doses taken orally and received by injection will be recorded
