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Description
In addition, Shc3 activates the -catenin/T-cell factor (TCF) pathway by interacting with the cytoplasmic components of -catenin, which reduces -catenin degradation and increases the expression of MDR1 (multidrug resistance 1) in HCC, resulting in multidrug resistance [137]
2000 Influence of the cellular redox state on NF-kappaB-regulated gene expression J
doi: 10.1186/gb-2002-3-7-research0034 20 HellemansJMortierGde PaepeASpelemanFVandesompeleJ
doi: 10.1038/s41586-018-0694-x
The platform exhibited good stability and biocompatibility as well as higher anticancer activity compared to the free drug [136]
Since it is a neuromodulator, it blocks the nerve signals to your muscles temporarily
