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In the initial stages of obesity, the uptake of fatty acids and glucose by adipocytes leads to the activation of NOX4, the major isoform of NADPH oxidase found in adipocytes, resulting in the increased production of ROS [57,58,59]

doi: 10.1183/09031936.03.00040703 38 LiYZhangLPolverinoFGuoFHaoYLaoTet al

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These results indicated that C75 effectively inhibited lipid metabolism disorders in SHR

CKMT1 and NCOA1 expression as a predictor of clinical outcome in patients with advanced-stage head and neck squamous cell carcinoma