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2 Safety of FIRDAPSE was evaluated in pediatric patients in an expanded access program in which 21 pediatric patients received FIRDAPSE for at least 1 year

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The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition. Nature Cell Biology , 17(12), 1523-1535

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Preclinical studies report higher mitochondrial DNA copy numbers and elevated respiratory enzyme levels in muscle tissue, correlating with increased VOmax and reduced fatigue in rodent exercise tests

Gurney, M