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The ECM is a dynamic structure that provides mechanical support and regulates cellular behavior through biochemical and mechanical cues
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GHK-Cu counteracts these effects, with studies showing

2012 GHK-Cu may prevent oxidative stress in skin by regulating copper and modifying expression of numerous antioxidant genes Cosmetics Study demonstrating GHK-Cu's regulation of antioxidant gene expression and copper-dependent protective mechanisms in skin tissue

For the compilation of previous literatures, the inclusion and exclusion criteria have been used

10.1111/exd.12579 Exp Dermatol
