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Macrophage activation and foam cell formation may explain the elevated CRP serum levels and contribute to disease progression (Figure 9)

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Additionally, in bivalves, these processes may be regulated by peroxisome proliferator-activated receptors (PPARs) and retinoid X receptors (RXRs) [544,545], which are nuclear transcription factors well-known for their roles in mammalian lipid metabolism (refer to our review [130])

doi: 10.3109/01485019008987590 52 KrassasGEPapadopoulouFTziomalosKZeginiadouTPontikidesN

However, results vary from person to person based on skin type, dosage, and consistency of sessions