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Suitable for both adults and children (as prescribed by a healthcare professional)

A study of comprehensive structureactivity relationships (SARs) revealed that quinolinium analogues inhibit NNMT at low concentrations and selectively bind to the NNMT substrate-binding site residues (99)

There are other large RCTs where similarly high doses of vitamin B 12 have been given together with other micronutrients

How do vitamin B12 shots work

When NNMT activity is elevated as documented in obese adipose tissue, several cancer types, and aged skeletal muscle intracellular NAD+ availability decreases, SAM availability decreases, and downstream sirtuin activity (particularly SIRT1 and SIRT3) is reduced

If a multi-dose vial is opened, discard per protocol to avoid contamination