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Certain information about physicochemical properties and chromatographic behaviors of NAC and Di-NAC was obtained from literature studies

Nobel lecture, December 11, 1953

As an alternative to HPLC, ion exchange chromatography also could be performed

Although positive effects of NAC have been reported for treatments of patients with acute liver failure [61], other studies on acute liver failure and liver surgery suggest patients randomized to postoperative NAC received no benefit [62,63,64]

also known as rhodanese) to incorporate sulfur into cyanide ion, (CN ), thereby detoxifying the cyanide to thiocyanate

In this review, the multiple pharmacological effects of ISA, including antibacterial, antitumor, antifungal, anti-inflammatory, neuroprotective activities, and associated mechanisms were outlined (Figure 3)