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Similarly, Tsuji et al

Consequently, most pHresponsive photosensitizers are designed to be activated around pH 5.0 (Table 2) through three predominant means: 1) incorporation of pHresponsive ionizable groups that facilitate quenching through PeT, 2) pHlabile FRET linkers, and 3) pHdependent assembly/conformation of photosensitizer nanoassemblies, whereby strategy 3 is often combined with 1 or 2 via aPS nanoassembly

The Nrf2/SKN-1-dependent glutathione S-transferase pi homologue GST-1 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of manganism