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could also demonstrate a ROS-mediated cell death of mesenchymal cells due to iron overload mediated by the AMPK/MFF/DNM1L pathway triggering mitochondrial fragmentation and reducing ATP production (106)

confirmed that a dietary deficiency in vitamin E could disrupt glutathione homeostasis, thereby increasing gallstone risk [20]

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While B12 shots can benefit those with deficiencies or absorption issues, its important to note that they may not provide significant benefits for individuals with adequate B12 levels