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[1] The medication acts on receptors in the brain's appetite centers, particularly the hypothalamus, to reduce hunger and increase feelings of fullness after eating

It was reported that welldesigned biomimetic nanodrug delivery system encapsulating naringeninsignificantly enhanced bloodbrain barrier permeability and neuronal uptake (Yang et al

However, if it improves your adherence and tolerability, the theoretical pharmacokinetic disadvantage may not matter practically

532 The CNS may compensate for the impaired proprioceptive input from the knee by increasing activation in the hip abductors and core muscles, leading to abnormal kinematic patterns such as increased trunk sway, hip adduction, and pelvic drop

R., Erdjument-Bromage, H., et al

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