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This is accompanied by excessive activation of IRE1, indicating that the loss of XBP1 triggers dysregulation of IRE1, thereby promoting liver injury (Duwaerts et al., 2021)

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Notably, DSF/Cu enhanced T cell-mediated tumor cell killing in a dose-dependent manner (Supplementary Figure S7)

Accumulating evidence shows that inhibitors of glutamine metabolism, such as V-9302, JHU-083, and CB-839, elicit stronger antitumor effects when used in combination with immune checkpoint inhibitors 144,145,146 (Fig

Since younger people are widely considered the major carriers and spreaders of SARS-Cov-2, effective vaccines are still desperately needed to reduce virus transmission