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When -MSH binds to MC1R, it triggers the production of intracellular cAMP, which activates protein kinases C and A, leading to the activation of the MAPK and JAK-STAT pathways
doi: 10.1126/sciadv.adc8917
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10.1016/j.asjsur.2023.05.096 55
Agudo-Canalejo, R
