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AgRP neurons do so through projections to the paraventricular hypothalamus (PVH), where, in a mechanism not previously described for AgRP neurons, they presynaptically inhibit the terminals of tonically active GABAergic afferents from the bed nucleus of the stria terminalis (BNST) that otherwise restrain activity of corticotrophin-releasing hormone (CRH)-expressing neurons

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PM2.5 particles, measuring less than 2.5 micrometers in diameter, are small enough to penetrate the skin barrier and reach deeper layers where they can cause cellular damage

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both stoppers sterilized with separate swabs