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It is strictly required for the function of the Pyruvate Dehydrogenase (PDH) complex, which acts as the critical bridge connecting glycolysis to the Krebs cycle (the primary engine of cellular respiration)

***Aunque con la intervencin siguieron con cifras por arriba de lo recomendado, en un 76% hubo disminucin de las cifras en un rango de 12-54 mg/dL

TMA/TMAO in hypertension: novel horizons and potential therapies

In fact, a key parameter omitted in the trials with deferiprone was that the iron chelator was not targeted to the mitochondria, so effectively only a small fraction of the compound delivered would accumulate in the principal site of damage under these conditions

, Bauditz J., Swidsinski A., et al