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Together, their findings indicate that ethanol exposure negatively affects GTPases that have accessory roles in lysosome function

Thus, aberrant CS activation in pregnant women and their placentae may induce endothelial damage that may cause hypertension and elevate circulating endothelial cells, further aggravating the CS, predisposing them to preeclampsia, and increasing its severity (476, 477)

The authors agree that this requires further largescale trials and cannot be claimed superior to the existing first-line conventional therapies

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