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Pavlopoulou, A

Although the pharmacology of VPA is still not understood completely, the drug seems to enhance activity of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), impair activity of the excitatory neurotransmitter glutamate, and block sodium channels

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Binding of the samples to the beads was done in a solution of 1 TBS (pH 8.0), 0.3% NP-40, 20% glycerol, 0.215 mM EDTA (pH 8.0), 150 mM KCl, at 4 C under agitation from 1 h to overnight

doi: 10.1176/appi.ajp.162.5.977CrossRefGoogle Scholar Lau, T., Bigio, B., Zelli, D., McEwen, B