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Description
In TNF--stimulated HUVECs and human aortic endothelial cells, sulforaphane has inhibited the induced phosphorylation of IB kinase (IKK) and IB-, as well as the binding of NF-B to binding sites in the LIPG gene [126]
[DOI] [PMC free article] [PubMed] [Google Scholar] 3.Rossignol D.A., Frye R.E
Studies report modulation of NO synthase activity and interaction with NO-mediated tissue protection pathways, which may underlie its broad cytoprotective profile
Free Radic Biol Med 45:16821694
Conversely, expressing15-PGDH in young mice causes their muscles to shrink and weaken
EV: empty vector
