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Thus, the clinical threshold for nephrotoxicity is determined by the balance between the rate of necrosis and the rate of regeneration of proximal tubular cells (Soberon et al., 1979)

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Making them involves special chemicals called coupling agents, which can trigger serious allergic reactions, including anaphylaxis a life-threatening condition

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Br J Pharmacol 121:17351743 Cruickshank CC, Dyer KR (2009) A review of the clinical pharmacology of methamphetamine

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