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10.1016/j.jot.2020.09.006 119 YuH.SongZ.YuJ.RenB.DongY.YouY.et al (2024)

This bidirectional interaction creates a vicious cycle that amplifies endothelial dysfunction, myocardial fibrosis, impaired energetics, and the progression of both HFpEF and HFrEF

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Similarly, gavage administration of EGCG yielded comparable results: mice exhibited hepatic congestion and a slight elevation in ALT levels after receiving 750 mg/kg/day of EGCG for 5 consecutive days (228)

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Antioxid Redox Signal 23(14):11711185