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Furthermore, the hippocampal metabolomic analysis indicated that sleep deprivation affected the metabolism of fatty acid and oxylipins, upregulated the tryptophan-kynurenine metabolic pathway, and exhibited a significant correlation with anxiety and depressive behaviors

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Clinical studies have investigated the effects of L-glutathione on skin lightening, and have found that supplementation with L-glutathione can lead to significant reductions in skin melanin index and skin darkening, as well as improvements in skin brightness and radiance