glutathione formaldehyde dehydrogenase Amino acid dependent metabolism in mammals Engineering Formaldehyde Dehydrogenase from Pseudomonas

doi: 10.1016/S0024-3205(00)01025-0

Taken together, under normal conditions, APAP-induced cell death involves peroxynitrite-mediated mitochondrial dysfunction but LPO and ferroptosis are unlikely to play a relevant role in the pathophysiology

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Factors responsible for the induction of ferroptosis may directly or indirectly affect glutathione peroxidases

The peptide also upregulates BRCA1, PTEN, and multiple other tumor suppressors

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