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[DOI] [PubMed] [Google Scholar] 11.Mischley LK, Lau RC, Shankland EG, Wilbur TK, Padowski JM

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Additionally, HIF-triggered metabolic reprogramming led to sorafenib resistance in several hepatocellular carcinoma (HCC) cell lines (Bao and Wong, 2021)

De Marinis, L., Mancini, A., Valle, D., Izzi, D., Bianchi, A., Gentilella, R., Giampietro, A., Desenzani, P., & Giustina, A

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While numerous synthetic ARIs have demonstrated excellent inhibition and shown promising results in animal studies, their efficacy in clinical trials was not very encouraging with some ARIs exhibiting adverse side effects