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Currently, APAP protein adduct formation and release into the circulation is being utilized as a biomarker for APAP overdose (O'Malley et al., 2015)

Ferroptosis is suppressed when a myristoylated version of ferroptosis suppressor protein 1 (FSP1) is recruited to the plasma membrane where it can reduce CoQ 10 to a lipophilic antioxidant that traps lipid peroxides

Levenes test will be performed to assess the homogeneity of variances within groups

doi: 10.1016/S0166-2236(97)01188-0 129 McCombM.BrowneR

Chung WK, Martin K, Jalas C, Braddock SR, Juusola J, Monaghan KG, Warner B, Franks S, Yudkoff M, Lulis L, Rhodes RH, Prasad V, Torti E, Cho MT, Shinawi M

In addition, the subcellular distribution of GFP labeled DAF-16 was detected, and the interaction between sappanone A and HSP-90 protein was mimicked by molecular docking