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However, remyelination was slightly delayed in mice lacking LtR (Plant et al., 2007)

( A - C ) Same UMAP of the myogenic subset as in Fig

Like fingolimod, siponimod is a modulator of the sphingosine-1-phosphate receptor with specific affinity for S1PR types 1 and 5

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Updated May 28, 2025

While hGH did produce a slight increase in glycerol in the knockout mice, the response was markedly lower than in WT animals
