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Rescue of early bace-1 and Global dna demethylation by S-Adenosylmethionine reduces amyloid pathology and improves cognition in an alzheimer's model

Zhao S, Zhou J, Chen R, Zhou W, Geng H, Huang Y, Shi S, Yuan L, Wang Z, Wang D

Constructing a codon-randomized CBS variant library A library of CBS variants was constructed using an oligo-directed codon-randomization mutagenesis method (Precision Oligo-Pool based Code Alteration or POPCode) [11]

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GLP-1 -receptor activation curbs appetite, slows gastric emptying and boosts glucose-dependent insulin release together these cut food intake and steady blood sugar [5] [8]
