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Vitamin B12, also known as cobalamin, is an essential water-soluble vitamin

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To demonstrate the role of GSH in chemotherapy resistance, we analyzed transcriptomic data from chemotherapy patient samples in the GEO database and collected post-chemotherapy samples from patients who underwent neoadjuvant chemotherapy, assessing the expression levels of GSH and GSH synthesis-related antioxidant enzymes

hexachlorophene and benserazide) that were already clinically available were tested and repurposed as CBS inhibitors (with the knowledge that they were not specific for CBS)

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The amount in the brain is seen to be higher in AD