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Aber auch diese Synthese-Wege reichen in der Regel nicht aus

Cytosolic NADH can freely diffuse through the porous mitochondrial outer membrane

[3] Bossak-Ahmad, K., Winiewska, M

The rate of synthesis, regeneration, and recycling is determined primarily by 3 factors8: De novo glutathione synthesis is primarily controlled by the cellular level of the amino acid cysteine, the availability of which is the rate-limiting step

Furthermore, the combination of manganese chloride and biotin has been found to upregulate brain CYP1B1 expression and reduce neurotoxicity, indicating a protective effect on neurotransmitter regulation and cerebrovascular homeostasis (59)

S., Koefoed A