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Abstract The purpose of this study was to investigate the utility of plasma pharmacokinetic and pharmacodynamic measures including plasma deoxynucleosides, homocysteine and methylmalonic acid concentrations in understanding the time course and extent of the inhibition of thymidylate synthase (TS) by pemetrexed in the context of a phase I/II combination study with vinorelbine

Bacteriostatic Water is a sterile, non-pyrogenic preparation of water for injection containing 0.9% benzyl alcohol as a bacteriostatic preservative

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Bleomycin-induced skin fibrosis in mice was similarly accompanied by upregulation of CD38 (Fig

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How PlexusDx Supports a More Personalized Approach PlexusDx's Precision Peptide Genetic Test may help provide context around metabolic variants affecting B12 utilization and methylation capacity