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The mechanistic conclusion is the same in both cases: overlapping GLP-1 agonism is redundant, so a researcher runs one comprehensive compound rather than two

Mynott TL, Ladhams A, Scarmato P, Engwerda CR

Nature (2019) 575:6938

M1 macrophages are activated by CS, bacterial products, and DAMPs, and secrete pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-) and interleukin-6 (IL-6) (87)

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Inhibiting tyrosinase enzymes whitens the skin by stopping the production of eumelanin and increasing the production of pheomelanin
