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A and tau are classical markers of AD, and disruption of BBB also worsens AD by causing their deposition

L-theanine , an amino acid derived from green tea, promotes a state of calm without sedation and may help regulate the nervous system in early recovery phases

Cell 76 , 969976 (1994)

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Additionally, NSW affects methylation of immune-modulatory genes and human endogenous retroviral elements such as ERVFRD-1, HERV-L, and HERV-P, indicating combined effects of circadian and metabolic stressors on immune epigenetic regulation 234

Physiol Plant 172:748761
