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PMCID: PMC7401279

This allows it to readily cross the blood-brain barrier (BRR) and offer neuroprotective, neurotrophic and antioxidant properties

This leads to pulmonary congestion and edema (fluid accumulation in the lungs)

It varies in severity from mild discomfort to extremely rare cases of withdrawal

They state: In sum, it seems that the effect of L-carnitine on TG and LDL-C depends on the health condition of individuals, so the patients with metabolic disorders and T2DM have had the most beneficial efficiency of this supplementation. They explain that some contradictory results in previous meta-analyses are attributed to differences in participant characteristics, study duration, and L-carnitine supplementation regimens