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2022 Sep;25(9):11341148

We first confirmed the dynamic profile of the PPP during chondrocyte differentiation by immunohistological staining of glucose-6-phosphate dehydrogenase (G6PDH), the rate-limiting enzyme of the PPP

These tests look for specific drug metabolites - the byproducts created when the body processes drugs

Here is where it gets interesting

The administration of fisetin (40 M) and sorafenib (5 M) for 24 h significantly reduced the viability of human cervical cancer HeLa cells, reaching approximately 20% compared to the control group [139]

60 Additionally, a decrease in the activity of SOD and GPx has been reported in patients with various types of cancer, and this reduction has been implicated in an increased risk of cancer and poor prognosis