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[DOI] [PMC free article] [PubMed] [Google Scholar] 213.Wakabayashi N., Dinkova-Kostova A

PEM and orthostatic intolerance, including POTS, are recognized as cardinal symptoms in ME/CFS patients (Committee on the Diagnostic Criteria for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

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Overall, expression levels of IL-2 and IFN were significantly higher in female-sex-derived immune cells, whereas male-sex-derived immune cells expressed significantly higher amounts of TNF-, an inflammatory cytokine that induces apoptosis [64]

It also lays the groundwork for the subsequent discussion on clinical implications and research gaps presented in Section 9

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