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Behr et al
Therefore, mutations in the PLPBP gene disrupt this process, causing PLP to react with other substrates and impacting the metabolism of important amine or amino acid neurotransmitters in the brain, consequently leading to the development of epilepsy
People over 50 are most at risk because your gut absorbs less B12 as you age
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Thus, cells deficient in SMARCA4, SMARCB1 or PBRM1 have low levels of GSH, making the cells vulnerable to ROS (Fig
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