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Why the shift

doi: 10.1002/alz.083000 162 ChangJLHinrichAJRomanBNorrbomMRigoFMarrRAet al

However, it is important to note that GSH is in equilibrium with GSSG and that this delicate balance is maintained via a complex multi-protein system containing the GSH synthesis proteins

633 Chronic social defeat stress-induced depressed mice showed iron accumulation and iron homeostasis imbalance in the brain, accompanied by downregulation of GSH levels and GPX4 expression, which may be a potential mechanism of lipid peroxidation and ferroptosis in depressed mice

doi: 10.1097/00007611-198411000-00007 141 TobiMMoragARavidZChowersIFeldman-WeissVMichaeliYet al

Intriguingly, the conversion from CD44 low to CD44 high was along with a shift from CD44s to CD44v, rather than a shift from non-CSCs to CSCs [110]
