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Cell pellets were resuspended in ice-cold buffer (2530 mL/L) containing 150 mM NaCl, 20 mM Tris (pH 8.0) and 1X Protease Inhibitors Cocktail (Roche)
Research indicates that the GLP-1 receptor agonist exenatide (Exendin-4) exhibits significant anti-inflammatory effects in neurodegenerative diseases, can clear pathological -syn through autophagy, and alleviates motor deficits induced by PD [165, 166]
doi: 10.1083/jcb.200706187
GSE241914
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