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Spider angioma, involving central arterioles surrounded by radiating capillaries, occurs in 33% of alcohol-associated cirrhosis cases and is also linked to hepatopulmonary syndrome, arising from increased blood flow to the surface capillaries

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evaluated the plasma L-carnitine levels of subjects with high levels of TMAO ( n = 2,595) and found that the intake of large amounts of L-carnitine caused cardiovascular disease (CVD) and major adverse cardiac events (MI, stroke, or death)

In mice with NAFLD, several related gene expression disorders were recovered by betaine supplementation (Reference Xu, Huang and Hu36)

Future Journal of Pharmaceutical Sciences, 10 , Article 22

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