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Figure 8 4.2 Polymeric nanoparticles Polymeric NPs are organic compounds composed of biocompatible and biodegradable polymers like polylactic acid (PLA) and polyglycolic acid (PGA) (92)

22 Interestingly, the disruption to EC junctions seems to be repaired after paracellular extravasation, without significant damage to the BBB

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Copper Ion (Cu): Copper plays a vital role in various biological processes, including antioxidant defense, collagen and elastin synthesis, and the integrity of blood vessels

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