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W.et al (2015)

MOLDOVAN M

Glutamate receptor overactivation leads to several detrimental results, such as cellular calcium homeostasis impairment, free radical overproduction, and oxidative toxic stress induction, increasing mitochondrial permeability transition, triggering several transcription factors and their gene expression and secondary excitotoxicity

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These outcomes align with similar results observed in other marine and freshwater fish species, as largemouth bass ( Micropterus salmoides ), grass carp ( Ctenopharyngodon idella ), and giant croaker ( Nibea japonica ), where high-fat diets led to a lower final body weight gain compared to diets with normal fat levels 37,38