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10.1002/pdi.2067 41

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Although neurons activate compensatory NAD + salvage through nicotinamide phosphoribosyltransferase (NAMPT) [108], this pathway fails to offset PARP-1-driven NAD + catabolism during stroke [106], resulting in sustained sirtuin suppression and disrupted mitochondrial dynamics

Figure 1 Discussion In this paper, we aimed to evaluate whether the innovative crawling software NPSfinder can be employed as a helpful tool in the early identification and prediction of CEs