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Notably, there is functional crosstalk between metabolic reprogramming and DNA damage repair pathways [61]

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doi: 10.1093/brain/124.10.2014 29 CampbellD

doi: 10.1007/s12038-009-0100-9

In addition, our preliminary study showed that maternal diabetes induces significantly decreased expression of SOD2 and ER in brain, resulting in more severe ALBs in male offspring compared to female offspring since male offspring have relatively much lower basal ER expression in brain, making male offspring more susceptible to hyperglycemia-induced damage

It is also used as a whitener because of its ability to to inhibit the melanin synthesis
